(19)
(11) EP 4 798 725 A1

(12)

(43) Date of publication:
02.09.2026 Bulletin 2026/36

(21) Application number: 24794800.3

(22) Date of filing: 24.10.2024
(51) International Patent Classification (IPC): 
C12N 15/86(2006.01)
C12N 15/864(2006.01)
 C12N 15/861(2006.01)
C07K 14/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/86; C07K 2317/569; C07K 2319/33; C07K 16/40; C07K 16/2896; C07K 14/005; C12N 2750/14122; C12N 2750/14145
(86) International application number:
PCT/EP2024/080156
(87) International publication number:
WO 2025/088080 (01.05.2025 Gazette 2025/18)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 24.10.2023 EP 23205665

(71) Applicants:
  • Universitätsklinikum Hamburg-Eppendorf
    20246 Hamburg (DE)
  • Revvity Gene Delivery GmbH
    82166 Gräfelfing (DE)

(72) Inventors:
  • SALOMON, Michael Otto
    82166 Gräfelfing (DE)
  • THIRION, Christian Olivier
    82166 Gräfelfing (DE)
  • NOLTE, Friedrich
    20246 Hamburg (DE)
  • MANN, Anna Marei
    20246 Hamburg (DE)
  • SCHÄFER, Waldemar
    20246 Hamburg (DE)

(74) Representative: Maiwald GmbH 
Elisenhof Elisenstraße 3
80335 München
80335 München (DE)

   


(54) SURFACE MARKER BINDING DOMAIN INSERT IN VP3 CAPSID PROTEIN OF AAV AND METHOD FOR PRODUCING RECOMBINANT AAV