(19)

(11)

EP 4 798 726 A1

(12)

(43) Date of publication: 02.09.2026 Bulletin 2026/36 (21) Application number: 24795193.2 (22) Date of filing: 25.10.2024

(51) International Patent Classification (IPC):  C12N 15/86(2006.01) A61K 39/00(2006.01) A61K 38/00(2006.01) C12N 15/67(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/86; C12N 2770/36143; C12N 15/67; A61K 38/00; C12N 2830/50; C12N 15/88; A61K 39/12; A61K 2039/53; A61K 2039/54; A61K 2039/545; A61K 2039/55555 (86) International application number: PCT/EP2024/080284 (87) International publication number: WO 2025/088152 (01.05.2025 Gazette 2025/18)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.10.2023 EP 23206532 (71) Applicant: ZIPHIUS NV 9052 Zwijnaarde (BE)	(72) Inventor: MENG, Zhao 9052 Zwijnaarde (BE) (74) Representative: Brantsandpatents bv  Pauline Van Pottelsberghelaan 24 9051 Ghent 9051 Ghent (BE)