(19)

(11)

EP 4 815 919 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24833744.6 (22) Date of filing: 20.12.2024

(51) International Patent Classification (IPC):  A61K 9/06(2006.01) A61K 47/02(2006.01) A61K 38/16(2006.01) A61P 25/32(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/06; A61K 47/02; A61P 25/32; A61K 38/1722 (86) International application number: PCT/EP2024/088046 (87) International publication number: WO 2025/157554 (31.07.2025 Gazette 2025/31)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 23.01.2024 EP 24153321 (71) Applicants: ETH Zurich 8092 Zürich (CH) Universiteit Gent 9000 Gent (BE)	(72) Inventors: SU, Jiaqi 8006 Zurich (CH) MEZZENGA, Raffaele 8604 Volketswil (CH) (74) Representative: E. Blum & Co. AG  Franklinturm Hofwiesenstrasse 349 8050 Zürich 8050 Zürich (CH)