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EP 4 815 927 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898807.3 (22) Date of filing: 27.11.2024

(51) International Patent Classification (IPC):  A61K 9/51(2006.01) A61K 48/00(2006.01) A61P 11/00(2006.01) A61K 9/00(2006.01) A61K 31/7105(2006.01) (52) Cooperative Patent Classification (CPC): C12Q 1/6806; C12N 15/10 (86) International application number: PCT/US2024/057849 (87) International publication number: WO 2025/117815 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 US 202363605181 P (71) Applicant: Recode Therapeutics, Inc. Menlo Park, CA 94025 (US)

(72) Inventors: HENNIG, Mirko Menlo Park, CA 94025 (US) MOHAPATRA, Sakya, Sing Menlo Park, CA 94025 (US) ISHIMARU, Daniella Menlo Park, CA 94025 (US) CEFALU, Joseph, S. Menlo Park, CA 94025 (US) ALFAIFI, Ali, Ahmed Menlo Park, CA 94025 (US) BAEK, Julia, Jung-un Menlo Park, CA 94025 (US) MENG, Hu Menlo Park, CA 94025 (US) MONROE, Jeremy Menlo Park, CA 94025 (US) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)