(19)
(11) EP 4 815 939 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24898736.4

(22) Date of filing: 27.11.2024
(51) International Patent Classification (IPC): 
A61K 31/395(2006.01)
A61K 31/517(2006.01)
A61K 31/33(2006.01)
 A61K 31/495(2006.01)
A61K 31/18(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 45/06; A61K 31/4375; A61K 31/519; C07D 519/00; C07D 471/04; A61P 35/00
 
C-Sets:
  1. A61K 31/4375, A61K 2300/00;
  2. A61K 31/519, A61K 2300/00;
(86) International application number:
PCT/US2024/057687
(87) International publication number:
WO 2025/117697 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 29.11.2023 US 202363603798 P

(71) Applicant: Riboscience LLC
Palo Alto, CA 94306 (US)

(72) Inventor:
  • HAWLEY, Ronald
    Palo Alto, California 94306 (US)

(74) Representative: J A Kemp LLP 
80 Turnmill Street
London EC1M 5QU
London EC1M 5QU (GB)

   


(54) 7-AZA BICYCLIC HETEROARYL DERIVATIVES AS ECTONUCLEOTIDE PYROPHOSPHATASE PHOSPHODIESTERASE 1 INHIBITORS