(19)

(11)

EP 4 815 940 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898845.3 (22) Date of filing: 29.11.2024

(51) International Patent Classification (IPC):  A61K 31/395(2006.01) A61K 31/13(2006.01) A61K 31/404(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/517; A61K 31/506; C07D 401/14; A61K 47/55 (86) International application number: PCT/US2024/057948 (87) International publication number: WO 2025/117878 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 US 202363605364 P (71) Applicant: Casma Therapeutics, Inc. Boston, Massachusetts 02115 (US)	(72) Inventors: MEREDITH, Erik Lee Cambridge, Massachusetts 02115 (US) KELLY, John Cambridge, Massachusetts 02115 (US) BAIRD, Daniel W. Cambridge, Massachusetts 02115 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)