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EP 4 815 962 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898905.5 (22) Date of filing: 02.12.2024

(51) International Patent Classification (IPC):  A61K 31/7056(2006.01) A61P 1/00(2006.01) C07D 309/10(2006.01) A61K 31/7034(2006.01) A61P 5/00(2006.01) C07D 405/12(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/7034; A61K 31/7056; A61P 1/00; A61P 5/00 (86) International application number: PCT/US2024/058107 (87) International publication number: WO 2025/117961 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 US 202363605203 P (71) Applicant: Vogenx Durham, NC 27713 (US)	(72) Inventors: WILKISON, William, Owen Raleigh, NC 27615 (US) GREEN, James, T. Raleigh, NC 27614 (US) CHEATHAM, Bentley Durham, NC 27705 (US) (74) Representative: Jacobi, Markus Alexander  Patentanwälte Isenbruck Bösl Hörschler PartG mbB Eastsite One Seckenheimer Landstrasse 4 68163 Mannheim 68163 Mannheim (DE)