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(11)

EP 4 815 968 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898585.5 (22) Date of filing: 25.11.2024

(51) International Patent Classification (IPC):  A61K 35/33(2015.01) A61K 39/39(2006.01) A61P 37/04(2006.01) A61K 9/127(2025.01) A61P 11/00(2006.01) C12N 5/0775(2010.01) (52) Cooperative Patent Classification (CPC): A61K 35/33; A61P 11/00; A61P 37/04; A61K 2039/515; A61K 39/0005; C12N 5/0656 (86) International application number: PCT/US2024/057294 (87) International publication number: WO 2025/117451 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.11.2023 US 202363602829 P (71) Applicant: FibroBiologics, Inc. Houston, Texas 77289 (US)	(72) Inventors: O'HEERON, Pete Houston, Texas 77059 (US) NEWLIN, Cindy Houston, Texas 77289 (US) ICHIM, Thomas San Diego, California 92122 (US) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)