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EP 4 815 977 A2

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(88) Date of publication A3: 31.07.2025 (43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24866579.6 (22) Date of filing: 25.11.2024

(51) International Patent Classification (IPC):  A61K 38/46(2006.01) A61K 8/66(2006.01) A61P 1/02(2006.01) A61K 38/48(2006.01) A61Q 11/00(2006.01) C07K 14/00(2006.01) (52) Cooperative Patent Classification (CPC): A61Q 11/00; A61K 8/66; A61K 38/482; A61K 38/465; A61P 1/02; C12Y 301/01081; C12Y 304/00; C12N 9/48; C12N 9/18 (86) International application number: PCT/CN2024/134130 (87) International publication number: WO 2025/113371 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 30.11.2023 WO PCT/CN2023/135359 (71) Applicant: Novozymes A/S 2880 Bagsværd (DK)	(72) Inventors: HUANG, Hong Zhi Beijing 100085 (CN) CAI, Xiangyu Beijing 100085 (CN) HOFF, Tine 2880 Bagsvaerd (DK) MORANT, Marc Dominique 2880 Bagsvaerd (DK) ZHANG, Ying Beijing 100085 (CN) (74) Representative: NVS EPO Representatives  Krogshoejvej 36 2880 Bagsvaerd 2880 Bagsvaerd (DK)