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EP 4 815 978 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898885.9 (22) Date of filing: 02.12.2024

(51) International Patent Classification (IPC):  A61K 38/46(2006.01) C12N 15/113(2010.01) C12N 9/22(2006.01) A61K 38/45(2006.01) A61K 48/00(2006.01) C12N 9/10(2006.01) A61K 38/16(2006.01) (52) Cooperative Patent Classification (CPC): C12N 15/113; C12N 15/85; C12N 2830/00; C12N 2830/003; C12N 2830/48; C12N 2740/16043; C12N 15/90; C12N 9/226; C07K 2319/00; C07K 2319/80; C12N 9/1007; C12N 15/62; C12N 15/52; C12N 2310/20; A61K 38/00 (86) International application number: PCT/US2024/058047 (87) International publication number: WO 2025/117934 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 US 202363604969 P 07.05.2024 US 202463643752 P (71) Applicant: Epitor Therapeutics New York, NY 10032 (US)	(72) Inventors: TSAI, Yi-Ting Englewood Cliffs, New Jersey 07632 (US) KIM, Dongkyeong Syracuse, New York 13210 (US) (74) Representative: MERH-IP Matias Erny Reichl Hoffmann Patentanwälte PartG mbB  Paul-Heyse-Straße 29 80336 München 80336 München (DE)