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EP 4 815 981 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24816960.9 (22) Date of filing: 29.11.2024

(51) International Patent Classification (IPC):  A61K 39/12(2006.01) A61P 31/14(2006.01) (52) Cooperative Patent Classification (CPC): A61K 39/12; A61K 2039/543; C12N 2770/20034; A61K 2039/541; C12N 2760/16134; A61K 2039/505; A61P 31/14; Y02A 50/30 (86) International application number: PCT/EP2024/084064 (87) International publication number: WO 2025/114521 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 EP 23213600 (71) Applicant: Forschungszentrum Borstel, Leibniz Lungenzentrum 23845 Borstel (DE)	(72) Inventors: FREY, Andreas 23816 Groß Niendorf (DE) FREY, Barbara 23816 Groß Niendorf (DE) RAMAKER, Katrin 22397 Hamburg (DE) RÖCKENDORF, Niels 22941 Bargteheide (DE) (74) Representative: Moré, Solveig Helga  Kroher Strobel Rechts- und Patentanwälte PartmbB Bavariaring 20 80336 München 80336 München (DE)