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(11)

EP 4 815 986 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898747.1 (22) Date of filing: 27.11.2024

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) C12Q 1/686(2018.01) (52) Cooperative Patent Classification (CPC): C12Q 1/686; C07K 16/40; C07K 2317/76   C-Sets: C12Q 1/686, C12Q 2527/127; (86) International application number: PCT/US2024/057713 (87) International publication number: WO 2025/117716 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 30.11.2023 US 202363604290 P (71) Applicant: Watchmaker Genomics, Inc. Boulder, Colorado 80301 (US)	(72) Inventors: VENTER, Phillip Boulder, CO 80301 (US) FAURHOLM, Bjarne Boulder, CO 80301 (US) DE BEER, Abré Boulder, CO 80301 (US) VAN DER WALT, Eric Boulder, CO 80301 (US) (74) Representative: Mewburn Ellis LLP  Aurora Building Counterslip Bristol BS1 6BX Bristol BS1 6BX (GB)