(19)
(11) EP 4 815 994 A2

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24809683.6

(22) Date of filing: 21.11.2024
(51) International Patent Classification (IPC): 
A61K 47/68(2017.01)
C07D 211/06(2006.01)
 A61P 35/00(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 47/6803; A61P 35/00; C07D 401/14
(86) International application number:
PCT/EP2024/083152
(87) International publication number:
WO 2025/109097 (30.05.2025 Gazette 2025/22)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 24.11.2023 EP 23212107

(71) Applicant: Heidelberg Pharma Research GmbH
68526 Ladenburg (DE)

(72) Inventors:
  • RUEDAS BATUECAS, Pablo
    68526 Ladenburg (DE)
  • GRUSS, Hendrik
    68526 Ladenburg (DE)
  • PÁLFI, Anikó
    68526 Ladenburg (DE)
  • NEUBERTH, Sarah-Jane
    68526 Ladenburg (DE)
  • HECHLER, Torsten
    68526 Ladenburg (DE)

   


(54) NOVEL NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE INHIBITORS AND USES THEREOF