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(11)

EP 4 816 057 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24817225.6 (22) Date of filing: 28.11.2024

(51) International Patent Classification (IPC):  A61P 25/00(2006.01) A61K 31/5517(2006.01) C07D 487/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 487/04; A61P 25/00 (86) International application number: PCT/EP2024/083843 (87) International publication number: WO 2025/114404 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 30.11.2023 EP 23213492 (71) Applicant: F. Hoffmann-La Roche AG 4070 Basel (CH)	(72) Inventors: BUTTAR, Suzanne Marie Edinburgh EH11 2QA (GB) PATTERSON, Adam Ross Edinburgh EH11 2QA (GB) STRATFORD, Samuel Alexander Edinburgh EH11 2QA (GB) (74) Representative: Graham Watt & Co  Fulwood House 12 Fulwood Place London WC1V 6HR London WC1V 6HR (GB)