(19)

(11)

EP 4 816 058 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24824660.5 (22) Date of filing: 26.11.2024

(51) International Patent Classification (IPC):  A61P 25/00(2006.01) C07K 16/28(2006.01) A61P 29/00(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/2887; C07K 2317/24; A61P 25/00; G16H 50/70; A61P 29/00; G16H 20/17; G16H 50/20 (86) International application number: PCT/US2024/057416 (87) International publication number: WO 2025/117516 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 30.11.2023 US 202363604675 P (71) Applicant: GENZYME CORPORATION Cambridge, Massachusetts 02141 (US)	(72) Inventor: MOLONY, Cliona Marie Cambridge, Massachusetts 02141 (US) (74) Representative: Ipsilon  12 Avenue d'Italie 75013 Paris 75013 Paris (FR)