(19)
(11) EP 4 816 060 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24786564.5

(22) Date of filing: 17.09.2024
(51) International Patent Classification (IPC): 
A61P 35/00(2006.01)
C07D 487/04(2006.01)
 A61P 37/02(2006.01)
A61K 31/519(2006.01)
(52) Cooperative Patent Classification (CPC):
C07D 487/04; A61P 35/00; A61P 37/02
(86) International application number:
PCT/IB2024/059009
(87) International publication number:
WO 2025/114771 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 29.11.2023 LV 230127

(71) Applicants:
  • Latvian Institute Of Organic Synthesis
    1006 Riga (LV)
  • Universitetet I Oslo
    0316 Oslo (NO)

(72) Inventors:
  • BOBROVS, Raitis
    2113 Plakanciems (LV)
  • TERENTJEVA, Svetlana
    1067 Riga (LV)
  • JIRGENSONS, Aigars
    1013 Riga (LV)
  • JAUDZEMS, Kristaps
    4101 Cesis (LV)
  • MATTHEWS, Jason
    0661 Oslo (NO)

(74) Representative: Meissner Bolte Nürnberg 
Patentanwälte Rechtsanwälte Partnerschaft mbB Bankgasse 3
90402 Nürnberg
90402 Nürnberg (DE)

   


(54) A NEW CLASS OF ARYL HYDROCARBON RECEPTOR ANTAGONISTS AND THEIR OPTIMISATION