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EP 4 816 062 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24817301.5 (22) Date of filing: 29.11.2024

(51) International Patent Classification (IPC):  A61P 35/00(2006.01) C07K 16/28(2006.01) C07K 16/32(2006.01) C07K 16/18(2006.01) C07K 16/30(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/18; C07K 16/2809; C07K 2317/569; C07K 2317/31; A61P 35/00; C07K 16/30; C07K 16/303; C07K 16/32; C07K 16/2863; C07K 16/3069; C07K 2317/92; C07K 2319/50; A61K 2039/505; C07K 2317/94; C07K 2317/73; C07K 2319/31 (86) International application number: PCT/EP2024/084075 (87) International publication number: WO 2025/114529 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 EP 23213660 (71) Applicant: Ablynx N.V. 9052 Zwijnaarde (BE)

(72) Inventors: BOUTTON, Carlo 9052 Ghent-Zwijnaarde (BE) DESCHAGHT, Pieter 9052 Ghent-Zwijnaarde (BE) FOUBERT, Ellen 9052 Ghent-Zwijnaarde (BE) NONNE, Christelle 9052 Ghent-Zwijnaarde (BE) ROOBROUCK, Annelies 9052 Ghent-Zwijnaarde (BE) STAELENS, Stephanie 9052 Ghent-Zwijnaarde (BE) (74) Representative: Hoffmann Eitle  Patent- und Rechtsanwälte PartmbB Arabellastraße 30 81925 München 81925 München (DE)