(19)

(11)

EP 4 816 351 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898641.6 (22) Date of filing: 26.11.2024

(51) International Patent Classification (IPC):  C07C 255/43(2006.01) A61P 25/28(2006.01) C07D 211/06(2006.01) A61P 25/16(2006.01) C07C 255/42(2006.01) G01N 33/68(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/16; A61P 25/28; C07D 295/155; G01N 33/6896; G01N 33/533 (86) International application number: PCT/US2024/057469 (87) International publication number: WO 2025/117551 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.11.2023 US 202363602881 P (71) Applicant: Amydis, Inc. Los Angeles, CA 90067 (US)	(72) Inventor: SARRAF, Stella Los Angeles, CA 90067 (US) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)