(19)

(11)

EP 4 816 352 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898711.7 (22) Date of filing: 27.11.2024

(51) International Patent Classification (IPC):  C07D 209/02(2006.01) A61K 31/165(2006.01) A61P 25/00(2006.01) C07D 217/00(2006.01) A61K 31/40(2006.01) (52) Cooperative Patent Classification (CPC): A61P 25/00; C07D 401/14; C07D 401/04; C07D 471/04; C07D 413/14; C07D 417/14; C07D 409/14; C07D 413/04; C07D 487/04; C07D 519/00 (86) International application number: PCT/US2024/057646 (87) International publication number: WO 2025/117662 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 29.11.2023 US 202363604173 P 14.02.2024 US 202463553526 P (71) Applicant: Actio Biosciences, Inc. San Diego, CA 92130 (US)	(72) Inventors: STOCK, Nicholas Simon Encinitas, California 92024 (US) GOVEK, Steven San Diego, California 92129 (US) KATANA, Ashley Fairview Park, OH 44126 (US) (74) Representative: Casalonga  Casalonga & Partners Bayerstraße 71/73 80335 München 80335 München (DE)