FORMS OF 3-(2-HYDROXY-2-METHYLPROPYL)-8-(PYRIDIN-3-YL)-6-(6-(TRIFLUOROMETHYL)PYRIDIN-3-YL)PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE - Patent 4816370

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EP 4 816 370 A1

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(43)	Date of publication:
	07.10.2026 Bulletin 2026/41

(21)	Application number: 24827539.8

(22)	Date of filing: 27.11.2024

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International Patent Classification (IPC):

C07D 471/04^(2006.01)
A61K 31/519^(2006.01)

A61P 35/00^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	C07D 471/04; A61P 35/00; C07B 2200/13

(86)	International application number:
	PCT/US2024/057668

(87)	International publication number:
	WO 2025/117680 (05.06.2025 Gazette 2025/23)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

01.12.2023 US 202363605265 P

(71)	Applicant: Flagship Pioneering Innovations VII, LLC
	Cambridge, MA 02142 (US)

(72)	Inventors:
	TIJANI, Rasheed O. Cambridge, Massachusetts 02142 (US) KUNAPARAJU, Vijay Cambridge, Massachusetts 02142 (US)

(74)	Representative: Carpmaels & Ransford LLP
	One Southampton Row London WC1B 5HA London WC1B 5HA (GB)

(54)	FORMS OF 3-(2-HYDROXY-2-METHYLPROPYL)-8-(PYRIDIN-3-YL)-6-(6-(TRIFLUOROMETHYL)PYRIDIN-3-YL)PYRIDO[3,4-D]PYRIMIDIN-4(3H)-ONE