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(11)

EP 4 816 379 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24895264.0 (22) Date of filing: 28.11.2024

(51) International Patent Classification (IPC):  C07H 19/056(2006.01) A61P 19/04(2006.01) A61K 31/7056(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61P 19/04; C07H 19/056; A61P 35/00; C07H 1/00 (86) International application number: PCT/CA2024/051579 (87) International publication number: WO 2025/111704 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 01.12.2023 US 202363605083 P (71) Applicant: Université Laval Québec, Québec G1V 0A6 (CA)	(72) Inventors: GIGUERE, Denis Québec G3A 3B4 (CA) ST-GELAIS, Jacob Longueuil, Québec J4N 1C4 (CA) LAGUE, Patrick Québec, Québec G1H 3M3 (CA) (74) Representative: Regimbeau  20, rue de Chazelles 75847 Paris Cedex 17 75847 Paris Cedex 17 (FR)