(19)
(11) EP 4 816 387 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24837294.8

(22) Date of filing: 29.11.2024
(51) International Patent Classification (IPC): 
C07K 14/47(2006.01)
A61K 38/17(2006.01)
C07K 14/475(2006.01)
C12N 15/86(2006.01)
 A61K 9/00(2006.01)
A61K 48/00(2006.01)
C07K 14/705(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 15/86; A61K 48/005; A61K 48/0075; C07K 14/47; C07K 14/4702; A61K 48/0058; C07K 14/475; C07K 14/705; A61K 9/0019; C07K 14/4705; C07K 14/4703; C07K 14/70571; C12N 2750/14143; C07K 14/805; C07K 14/4716; C07K 2319/00; A61K 47/02; A61K 9/08; A61K 9/0085; A61K 38/00
(86) International application number:
PCT/CN2024/135809
(87) International publication number:
WO 2025/113676 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 29.11.2023 WO PCT/CN2023/134880

(71) Applicants:
  • NEUEXCELL THERAPEUTICS (SUZHOU) CO., LTD.
    Suzhou, Jiangsu 215000 (CN)
  • Neuexcell Therapeutics Inc.
    Philadelphia, PA 19108 (US)

(72) Inventors:
  • ADDIS, Russell
    Philadelphia, PA 19108 (US)
  • KABANOVA, Anna
    Suzhou, Jiangsu 215000 (CN)
  • XU, Jie
    Suzhou, Jiangsu 215000 (CN)
  • CHEN, Gong
    Suzhou, Jiangsu 215000 (CN)
  • CHEN, Yuchen
    Suzhou, Jiangsu 215000 (CN)
  • CHEN, Ming
    Suzhou, Jiangsu 215000 (CN)

(74) Representative: Jones Day 
Gewürzmühlstr. 11
80538 München
80538 München (DE)

   


(54) COMPOSITIONS AND METHODS FOR TREATING STROKE IN PRIMATES