(19)
(11) EP 4 816 388 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 23833993.1

(22) Date of filing: 01.12.2023
(51) International Patent Classification (IPC): 
C07K 14/475(2006.01)
C12N 5/074(2010.01)
C12N 15/63(2006.01)
 C12N 5/0775(2010.01)
C12N 5/10(2006.01)
(52) Cooperative Patent Classification (CPC):
C12N 5/0696; C12N 5/0662; C07K 14/4753; C12N 15/63; C12N 15/907; C12N 2510/00; C12N 2506/45; C12N 2310/20
(86) International application number:
PCT/CN2023/135752
(87) International publication number:
WO 2025/112020 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
KH MA MD TN

(71) Applicant: Nuwacell Biotechnologies Co., Ltd.
Hefei, Anhui 230088 (CN)

(72) Inventors:
  • YU, Junying
    Hefei, Anhui 230088 (CN)
  • LI, Hailan
    Hefei, Anhui 230088 (CN)
  • SHAO, Wentao
    Hefei, Anhui 230088 (CN)
  • JIAO, Luyan
    Hefei, Anhui 230088 (CN)
  • ZHANG, Ying
    Hefei, Anhui 230088 (CN)

(74) Representative: Patentanwälte Magenbauer & Kollegen Partnerschaft mbB 
Plochinger Straße 109
73730 Esslingen
73730 Esslingen (DE)

   


(54) STEM CELLS MODIFIED WITH HEPATOCYTE GROWTH FACTOR, METHODS OF MAKING THE SAME AND METHODS OF USING THE SAME