(19)
(11) EP 4 816 399 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24817307.2

(22) Date of filing: 29.11.2024
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
A61P 35/00(2006.01)
 A61K 39/395(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/2818; C07K 16/2827; C07K 16/2878; A61K 2039/505; A61K 2039/507; C07K 2317/76; C07K 2317/73; A61P 35/00; C07K 2317/33; C07K 2317/92; C07K 2317/75; C07K 2317/94; C07K 2317/71
(86) International application number:
PCT/EP2024/084110
(87) International publication number:
WO 2025/114541 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 30.11.2023 EP 23213494
04.11.2024 EP 24210627

(71) Applicants:
  • Genmab A/S
    2500 Valby (DK)
  • BioNTech SE
    55131 Mainz (DE)

(72) Inventors:
  • KEMPER, Kristel
    3584 CT Utrecht (NL)
  • VAN DER KROEF, Maarten
    3584 CT Utrecht (NL)
  • VERZIJL, Dennis
    3584 CT Utrecht (NL)
  • GORLANI, Andrea
    3584 CT Utrecht (NL)
  • DE GOEJE, Pauline Linda
    3584 CT Utrecht (NL)
  • GUELEN, Lars
    3584 CT Utrecht (NL)
  • SATIJN, David
    3584 CT Utrecht (NL)
  • BREIJ, Esther, C, W,
    3584 CT Utrecht (NL)
  • SAHIN, Ugur
    55116 Mainz (DE)
  • FELLERMEIER-KOPF, Sina
    55131 Mainz (DE)
  • KÖHNE, Maren
    55131 Mainz (DE)
  • DIKS, Annieck
    3584 CT Utrecht (NL)
  • GARRIDO CASTRO, Patricia
    3584 CT Utrecht (NL)

(74) Representative: Genmab A/S 
Carl Jacobsens Vej 30
2500 Valby
2500 Valby (DK)

   


(54) ANTIBODIES CAPABLE OF BINDING TO OX40 IN COMBINATION THERAPY