(19)
(11) EP 4 816 401 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24817898.0

(22) Date of filing: 29.11.2024
(51) International Patent Classification (IPC): 
C07K 16/28(2006.01)
A61P 1/00(2006.01)
(52) Cooperative Patent Classification (CPC):
C07K 16/2896; C07K 2317/732; C07K 2317/72; C07K 2317/73; C07K 2317/76; C07K 2317/92; C07K 2317/94; A61P 1/00
(86) International application number:
PCT/EP2024/084141
(87) International publication number:
WO 2025/114555 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 30.11.2023 EP 23213466
05.11.2024 EP 24210868

(71) Applicant: OncoSpear ApS
8382 Hinnerup (DK)

(72) Inventors:
  • GRAVERSEN, Niels Jonas Heilskov
    8382 Hinnerup (DK)
  • JENSEN, Maria Pauladottir
    8382 Hinnerup (DK)
  • STRAUSS, Line Moesgaard
    8382 Hinnerup (DK)
  • HØGH, Rikke Illum
    8382 Hinnerup (DK)
  • MOULIN, Morgane Jennifer
    8382 Hinnerup (DK)
  • SKYTTHE, Maria Kløjgaard
    8382 Hinnerup (DK)
  • ETZERODT, Anders
    8382 Hinnerup (DK)

(74) Representative: Plougmann Vingtoft a/s 
Strandvejen 70
2900 Hellerup
2900 Hellerup (DK)

   


(54) ANTI-CD163 ANTIBODIES WITH IMPROVED ADCC CAPABILITIES