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EP 4 816 411 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898841.2 (22) Date of filing: 28.11.2024

(51) International Patent Classification (IPC):  C07K 16/30(2006.01) A61K 39/395(2006.01) A61K 47/68(2017.01) C07K 16/28(2006.01) C07K 16/32(2006.01) C07K 19/00(2006.01) A61K 38/02(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/32; C07K 2317/55; C07K 2317/31; C07K 2317/622; C07K 2317/92; C07K 2317/73; A61P 35/00; C07K 2317/76; C07K 2317/94; C07K 2317/567 (86) International application number: PCT/US2024/057936 (87) International publication number: WO 2025/117872 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 29.11.2023 US 202363604077 P (71) Applicant: SystImmune, Inc. Redmond WA 98052 (US)	(72) Inventors: RENSHAW, Blair Renton, WA 98058 (US) ZHU, Yi Redmond, WA 98052 (US) (74) Representative: Mathys & Squire  32 London Bridge Street The Shard London SE1 9SG London SE1 9SG (GB)