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EP 4 816 415 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24911410.9 (22) Date of filing: 27.12.2024

(51) International Patent Classification (IPC):  C07K 19/00(2006.01) A61P 35/00(2006.01) C12N 15/62(2006.01) A61K 39/395(2006.01) C07K 16/40(2006.01) C07K 16/32(2006.01) C12N 15/63(2006.01) C12N 15/13(2006.01) (52) Cooperative Patent Classification (CPC): A61P 35/00; C07K 16/40; C07K 2319/00; C07K 2319/31; C07K 2317/31; C07K 16/30; C07K 2317/22; C07K 2317/569; C07K 2317/52; C07K 2317/92; C07K 2317/94; C07K 2317/76; C07K 16/2809; C07K 2317/24; C07K 2317/73; C07K 2317/70; A61K 2039/505; C07K 2317/526; C07K 2317/60; C07K 16/2863 (86) International application number: PCT/CN2024/142997 (87) International publication number: WO 2025/140489 (03.07.2025 Gazette 2025/27)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 29.12.2023 WO PCT/CN2023/143088 (71) Applicant: Vibrant Pharma Limited Guangzhou, Guangdong 510000 (CN)	(72) Inventors: WANG, Luquan Guangzhou, Guangdong 510000 (CN) ZHOU, Changhua Guangzhou, Guangdong 510000 (CN) XIONG, Bojian Guangzhou, Guangdong 510000 (CN) SHI, Wanzhen Guangzhou, Guangdong 510000 (CN) (74) Representative: Fish & Richardson P.C.  Highlight Business Towers Mies-van-der-Rohe-Straße 8 80807 München 80807 München (DE)