(19)
(11) EP 4 816 514 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24824624.1

(22) Date of filing: 21.11.2024
(51) International Patent Classification (IPC): 
C12M 1/12(2006.01)
C12M 3/04(2006.01)
C12M 1/00(2006.01)
C12M 1/34(2006.01)
(52) Cooperative Patent Classification (CPC):
C12M 25/18; C12M 29/10; C12M 29/26; C12M 27/10; C12M 41/00
(86) International application number:
PCT/US2024/056861
(87) International publication number:
WO 2025/117320 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 30.11.2023 US 202363604534 P

(71) Applicant: Corning Incorporated
Corning, New York 14831 (US)

(72) Inventors:
  • GORAL, Vasiliy Nikolaevich
    Painted Post, New York 14870 (US)
  • HONG, Yulong
    Painted Post, New York 14870 (US)
  • SCHULTES, Joel Andrew
    Corning, New York 14830 (US)

(74) Representative: Elkington and Fife LLP 
Prospect House 8 Pembroke Road
Sevenoaks, Kent TN13 1XR
Sevenoaks, Kent TN13 1XR (GB)

   


(54) CELL CULTURE BIOREACTOR SYSTEM WITH BIDIRECTIONAL PERFUSION AND RELATED METHODS