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(11)

EP 4 816 533 A1

(12)

(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24887109.7 (22) Date of filing: 04.11.2024

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) A61K 31/7105(2006.01) A61K 31/12(2006.01) C12N 15/113(2010.01) A61K 31/711(2006.01) A61K 31/14(2006.01) (52) Cooperative Patent Classification (CPC): C12N 2310/11; C12N 15/1131; C12N 2320/31; A61K 45/06; A61K 31/7115; A61K 31/7088; G16B 35/10   C-Sets: A61K 31/7115, A61K 2300/00; A61K 31/7088, A61K 2300/00; (86) International application number: PCT/US2024/054396 (87) International publication number: WO 2025/097126 (08.05.2025 Gazette 2025/19)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 03.11.2023 US 202363596169 P (71) Applicant: Vionelix Pharmaceuticals, Inc. Raleigh, North Carolina 27601 (US)	(72) Inventor: AMIRAK, Emre Raleigh, North Carolina 27601 (US) (74) Representative: Handley, Matthew Edward et al Venner Shipley LLP St James's 79 Oxford Street Manchester M1 6EG Manchester M1 6EG (GB)