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EP 4 816 534 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24896556.8 (22) Date of filing: 27.11.2024

(51) International Patent Classification (IPC):  C12N 15/11(2006.01) A61K 31/713(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/713; C12N 15/113; C12N 2310/14   C-Sets: C12N 2310/321, C12N 2310/3521; C12N 2310/322, C12N 2310/3533; (86) International application number: PCT/CN2024/134773 (87) International publication number: WO 2025/113470 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 27.11.2023 WO PCT/CN2023/134234 (71) Applicant: Shanghai Argo Biopharmaceutical Co., Ltd. Shanghai 201803 (CN)	(72) Inventors: SHU, Dongxu Ningbo, Zhejiang 315100 (CN) SHAO, Pengcheng Patrick Warrington Township Pennsylvania 18976 (US) XIA, Shiwei Hangzhou, Zhejiang 311400 (CN) (74) Representative: Elkington and Fife LLP  Prospect House 8 Pembroke Road Sevenoaks, Kent TN13 1XR Sevenoaks, Kent TN13 1XR (GB)