(19)
(11) EP 4 816 550 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24828023.2

(22) Date of filing: 02.12.2024
(51) International Patent Classification (IPC): 
C12Q 1/6841(2018.01)
C12Q 1/6886(2018.01)
 C12Q 1/6869(2018.01)
(52) Cooperative Patent Classification (CPC):
C12Q 1/6841; C12Q 1/6886; C12Q 2600/106; C12Q 2600/158
 
C-Sets:
C12Q 1/6841, C12Q 2535/122, C12Q 2537/143, C12Q 2563/107, C12Q 2565/102;
(86) International application number:
PCT/EP2024/084353
(87) International publication number:
WO 2025/114609 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 01.12.2023 EP 23213776

(71) Applicant: MultiplexDX, s.r.o.
84104 Bratislava (SK)

(72) Inventors:
  • CEKAN, Pavol
    84104 Bratislava (SK)
  • PAUL, Evan
    84104 Bratislava (SK)
  • VALKOVÁ, Natália
    84104 Bratislava (SK)
  • HURAIOVÁ, Barbora
    84104 Bratislava (SK)
  • GALA, Michal
    84104 Bratislava (SK)

(74) Representative: Schiweck Weinzierl Koch Patentanwälte Partnerschaft mbB 
Ganghoferstraße 68 B
80339 München
80339 München (DE)

   


(54) METHOD FOR PREDICTING THE EFFICACY OF AN ANTIBODY-DRUG-CONJUGATE (ADC) USING MULTIPLEX FLUORESCENCE IN SITU HYBRIDIZATION (FISH) AND MULTIPLEX SEQUENCING