(19)
(11) EP 4 816 558 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24898814.9

(22) Date of filing: 27.11.2024
(51) International Patent Classification (IPC): 
C12Q 1/6883(2018.01)
C12Q 1/68(2018.01)
G01N 33/50(2006.01)
A61P 25/28(2006.01)
(52) Cooperative Patent Classification (CPC):
C12Q 1/6883; A61P 25/28; G01N 33/6896; G01N 2800/52; G01N 2800/385; G01N 2800/28; C12Q 2600/158; C12Q 2600/106
(86) International application number:
PCT/US2024/057864
(87) International publication number:
WO 2025/117826 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 30.11.2023 US 202363604513 P
23.09.2024 US 202463697927 P

(71) Applicant: Anavex Life Sciences Corp.
New York, NY 10111 (US)

(72) Inventor:
  • MISSLING, Christopher, U.
    New York, New York 10111 (US)

(74) Representative: SONN Patentanwälte GmbH & Co KG 
Riemergasse 14
1010 Wien
1010 Wien (AT)

   


(54) METHODS OF USING SURROGATE BIOMARKERS IN SIGMA-1 RECEPTOR THERAPY