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EP 4 816 561 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24896702.8 (22) Date of filing: 29.11.2024

(51) International Patent Classification (IPC):  C12Q 1/6886(2018.01) C12Q 1/6858(2018.01) C12Q 1/6869(2018.01) C12Q 1/68(2018.01) C12Q 1/6883(2018.01) G16B 20/00(2019.01) C12Q 1/6806(2018.01) (52) Cooperative Patent Classification (CPC): G16B 30/10; G16B 20/20; C12Q 2600/154; G16H 50/20; C12Q 1/6806; C12Q 1/6886; C12Q 1/6874; C12Q 1/686 (86) International application number: PCT/CN2024/135572 (87) International publication number: WO 2025/113619 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 29.11.2023 US 202363604167 P (71) Applicant: Centre for Novostics Hong Kong (HK)	(72) Inventors: LO, Yuk-Ming Dennis Hong Kong (CN) CHAN, Kwan Chee Hong Kong (CN) JIANG, Peiyong Hong Kong (CN) ZHOU, Qing Hong Kong (CN) PENG, Wenlei Hong Kong (CN) (74) Representative: J A Kemp LLP  80 Turnmill Street London EC1M 5QU London EC1M 5QU (GB)