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EP 4 816 803 A1

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(43) Date of publication: 07.10.2026 Bulletin 2026/41 (21) Application number: 24898897.4 (22) Date of filing: 02.12.2024

(51) International Patent Classification (IPC):  G01N 23/046(2018.01) G01N 23/04(2018.01) G01N 23/02(2006.01) G01T 1/29(2006.01) (52) Cooperative Patent Classification (CPC): A61K 49/0438; A61K 49/0485; A61K 49/049 (86) International application number: PCT/US2024/058084 (87) International publication number: WO 2025/117950 (05.06.2025 Gazette 2025/23)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 30.11.2023 US 202318524929 (71) Applicant: TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC Encino, CA 91436 (US)	(72) Inventor: TAFTI, Bashir, Akhavan Encino, CA 91436 (US) (74) Representative: Duncombe, Jessica et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)