(19)
(11) EP 4 816 820 A1

(12)

(43) Date of publication:
07.10.2026 Bulletin 2026/41

(21) Application number: 24809343.7

(22) Date of filing: 19.11.2024
(51) International Patent Classification (IPC): 
G01N 33/483(2006.01)
 G01N 21/00(2006.01)
(52) Cooperative Patent Classification (CPC):
G01N 33/4836
(86) International application number:
PCT/EP2024/082850
(87) International publication number:
WO 2025/114081 (05.06.2025 Gazette 2025/23)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 27.11.2023 EP 23212407

(71) Applicant: Deutsches Zentrum für Neurodegenerative Erkrankungen e.V. (DZNE)
53127 Bonn (DE)

(72) Inventors:
  • AMIN, Hayder
    01279 Dresden (DE)
  • KEMPERMANN, Gerd
    01309 Dresden (DE)

(74) Representative: Krauss, Jan 
SKM-IP PartGmbB Oberanger 45
80331 München
80331 München (DE)

   


(54) METHOD AND DEVICES FOR HIGH-RESOLUTION SPATIAL AND TEMPORAL MAPPING OF LARGE-SCALE ELECTROPHYSIOLOGICAL DYNAMICS AND TRANSCRIPTIONAL PROFILES WITHIN INTACT BRAIN TISSUES