(19)

(11)

EP 4 823 541 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24833781.8 (22) Date of filing: 13.12.2024

(51) International Patent Classification (IPC):  A61K 9/00(2006.01) A61K 31/519(2006.01) A61K 47/12(2006.01) A61P 35/00(2006.01) A61K 9/20(2006.01) A61K 47/02(2006.01) A61K 47/30(2006.01) (52) Cooperative Patent Classification (CPC): A61K 9/0053; A61K 9/20; A61K 9/2018; A61K 9/2054; A61K 9/2095; A61K 47/02; A61K 47/12; A61K 47/30; A61K 31/519; A61P 35/00 (86) International application number: PCT/IB2024/062632 (87) International publication number: WO 2025/126137 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 WO PCT/CN2023/138534 (71) Applicant: Johnson & Johnson Enterprise Innovation Inc. New Brunswick, NJ 08933 (US)	(72) Inventors: ZHU, Donghua Shanghai 200233 (CN) JI, Chongmin Shanghai 200233 (CN) (74) Representative: Carpmaels & Ransford LLP  One Southampton Row London WC1B 5HA London WC1B 5HA (GB)