TOPICAL COMPOSITION AND USE THEREOF TO REDUCE POST-SURGICAL USE OF OPIOIDS - Patent 4823559

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(11)

EP 4 823 559 A1

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(43)	Date of publication:
	21.10.2026 Bulletin 2026/43

(21)	Application number: 24901851.6

(22)	Date of filing: 10.12.2024

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International Patent Classification (IPC):

A61K 31/195^(2006.01)
A61K 9/06^(2006.01)
A61K 31/167^(2006.01)
A61P 23/02^(2006.01)
C07C 59/84^(2006.01)
C07C 229/34^(2006.01)

A61K 9/00^(2006.01)
A61K 31/135^(2006.01)
A61K 31/192^(2006.01)
A61P 29/00^(2006.01)
C07C 211/32^(2006.01)
C07C 237/04^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	A61K 31/135; A61K 31/167; A61K 31/192; A61P 23/02; A61P 29/00; A61K 9/0014; A61K 47/10; A61K 47/36; A61K 47/183; A61K 47/14; A61K 47/26; A61K 9/10; A61K 31/197

	C-Sets:
	A61K 31/135, A61K 2300/00; A61K 31/197, A61K 2300/00; A61K 31/167, A61K 2300/00; A61K 31/192, A61K 2300/00;

(86)	International application number:
	PCT/CA2024/051639

(87)	International publication number:
	WO 2025/123127 (19.06.2025 Gazette 2025/25)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

11.12.2023 US 202363608628 P

(71)	Applicant: KAZM Pharmaceuticals Inc.
	Hamilton, Ontario L9C 3B3 (CA)

(72)	Inventors:
	MUSITANO, Patrick Hamilton, Ontario L9C 3B3 (CA) ZALZAL, Paul Hamilton, Ontario L9C 3B3 (CA)

(74)	Representative: Sagittarius IP
	Marlow International Parkway Marlow SL7 1YL Marlow SL7 1YL (GB)

(54)	TOPICAL COMPOSITION AND USE THEREOF TO REDUCE POST-SURGICAL USE OF OPIOIDS