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EP 4 823 560 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24827078.7 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61K 31/225(2006.01) A61K 31/433(2006.01) A61K 31/495(2006.01) A61K 31/5025(2006.01) A61K 31/519(2006.01) A61K 31/713(2006.01) A61K 45/06(2006.01) A61K 31/277(2006.01) A61K 31/454(2006.01) A61K 31/502(2006.01) A61K 31/506(2006.01) A61K 31/7048(2006.01) A61K 38/14(2006.01) A61P 35/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/495; A61K 31/713; A61K 31/502; A61K 31/506; A61K 31/225; A61K 31/277; A61K 31/7048; A61K 31/519; A61K 31/433; A61K 31/5025; A61K 31/454; A61K 38/14; A61K 45/06; A61P 35/00   C-Sets: A61K 31/225, A61K 2300/00; A61K 31/277, A61K 2300/00; A61K 31/7048, A61K 2300/00; A61K 31/519, A61K 2300/00; A61K 31/433, A61K 2300/00; A61K 38/14, A61K 2300/00; A61K 31/495, A61K 2300/00; A61K 31/454, A61K 2300/00; A61K 31/713, A61K 2300/00; A61K 31/5025, A61K 2300/00; A61K 31/502, A61K 2300/00; A61K 31/506, A61K 2300/00; (86) International application number: PCT/EP2024/086059 (87) International publication number: WO 2025/125504 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 15.12.2023 EP 23216952 (71) Applicant: Eberhard Karls Universität Tübingen, Medizinische Fakultät 72074 Tübingen (DE)	(72) Inventors: TABATABAI, Ghazaleh 72076 Tuebingen (DE) HAEUSSER, Lara Annina 72070 Tuebingen (DE) TRAMPERT, Jil 72070 Tuebingen (DE) MERK, Daniel Josef Wolfgang 71134 Aidlingen (DE) KUHLBURGER, Laurence 72070 Tuebingen (DE) (74) Representative: Witte, Weller & Partner Patentanwälte mbB  Postfach 10 54 62 70047 Stuttgart 70047 Stuttgart (DE)