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EP 4 823 562 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24828778.1 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61K 31/341(2006.01) A61K 45/06(2006.01) A61K 9/48(2006.01) A61K 31/7076(2006.01) A61P 21/04(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/341; A61K 45/06; A61K 31/7076; A61P 21/04; A61K 9/4808; A61K 9/2054; A61K 9/2018   C-Sets: A61K 31/341, A61K 2300/00; A61K 31/7076, A61K 2300/00; (86) International application number: PCT/EP2024/086103 (87) International publication number: WO 2025/125527 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 14.12.2023 US 202363610175 P 10.06.2024 US 202463658170 P 06.08.2024 US 202463679861 P (71) Applicant: Ares Trading S.A. 1170 Aubonne, VD (CH)

(72) Inventors: BECKER, Andreas Werner 64293 Darmstadt (DE) RAVULA, Abhigyan Billerica, Massachusetts 01821 (US) GOTETI, Kosalaram Billerica, Massachusetts 01821 (US) ALEXANDRI, Nektaria 64293 Darmstadt (DE) BOSCHERT SHAFAATIAN, Ursula 1262 Eysins (CH) KOEHL, Niklas Julian 64293 Darmstadt (DE) VON BURKERSRODA, Friederike 64293 Darmstadt (DE) WIEDEY, Raphael 64293 Darmstadt (DE) ASSI, Pardis Craigavon Armagh BT63 5QD (GB) JUNG, Markus 64293 Darmstadt (DE) (74) Representative: Merck Serono S.A. Intellectual Property  Terre Bonne Business Park Building Z0 Route de Crassier 1 1262 Eysins 1262 Eysins (CH)