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(11)

EP 4 823 576 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24828283.2 (22) Date of filing: 09.12.2024

(51) International Patent Classification (IPC):  A61K 31/4725(2006.01) A61P 29/00(2006.01) A61P 1/00(2006.01) (52) Cooperative Patent Classification (CPC): A61K 31/4725; A61P 29/00; A61P 1/00 (86) International application number: PCT/US2024/059225 (87) International publication number: WO 2025/128492 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 11.12.2023 US 202363608750 P (71) Applicant: Gilead Sciences Inc. Foster City, California 94404 (US)	(72) Inventors: WEBER, Elijah J. San Francisco, California 94117 (US) OTHMAN, Ahmed A. Dublin, California 94568 (US) CHANG, Ingrid J. Denver, Colorado 80210 (US) MCKEVITT, Matthew T. Seattle, Washington 98144 (US) (74) Representative: Müller, Christian Stefan Gerd  ZSP Patentanwälte PartG mbB Hansastraße 32 80686 München 80686 München (DE)