ISTAROXIME AND METABOLITE DERIVATIVES THEREOF FOR REDUCING THE RISK OF ACUTE MYOCARDIAL ARRHYTHMIA - Patent 4823583

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EP 4 823 583 A1

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(43)	Date of publication:
	21.10.2026 Bulletin 2026/43

(21)	Application number: 24904669.9

(22)	Date of filing: 06.12.2024

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International Patent Classification (IPC):

A61K 31/566^(2006.01)
A61K 45/06^(2006.01)

A61K 31/58^(2006.01)
A61P 9/00^(2006.01)

(52)	Cooperative Patent Classification (CPC):
	A61P 9/00; A61K 31/58; A61K 45/06; A61K 31/5685

(86)	International application number:
	PCT/US2024/058923

(87)	International publication number:
	WO 2025/128432 (19.06.2025 Gazette 2025/25)

(84)	Designated Contracting States:
	AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
	Designated Extension States:
	BA
	Designated Validation States:
	GE KH MA MD TN

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Priority:

11.12.2023 US 202363608677 P

(71)	Applicant: Windtree Therapeutics, Inc.
	Warrington, PA 18976 (US)

(72)	Inventors:
	SIMONSON, Steven Kennett Square, PA 19348 (US) HSU, Shih-Che Taipai City, 114 (TW)

(74)	Representative: Kransell & Wennborg KB
	P.O. Box 27834 115 93 Stockholm 115 93 Stockholm (SE)

(54)	ISTAROXIME AND METABOLITE DERIVATIVES THEREOF FOR REDUCING THE RISK OF ACUTE MYOCARDIAL ARRHYTHMIA