(19)
(11) EP 4 823 592 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24828360.8

(22) Date of filing: 11.12.2024
(51) International Patent Classification (IPC): 
A61K 38/00(2006.01)
A61K 48/00(2006.01)
C12N 9/88(2006.01)
 A61K 38/51(2006.01)
C12N 9/10(2006.01)
C12N 15/86(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 48/005; C12N 15/86; A01K 2227/105; A61K 38/00; C12N 2800/22; A01K 2217/075; A61K 48/0058; C12N 2750/14143; C12N 9/0014; C12Y 104/04002
(86) International application number:
PCT/EP2024/085672
(87) International publication number:
WO 2025/125324 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 13.12.2023 GB 202319008

(71) Applicant: UCL Ventures Limited
London WC1E 6BT (GB)

(72) Inventors:
  • GREENE, Nicholas
    London Greater London WC1E 6BT (GB)
  • WADDINGTON, Simon
    London Greater London WC1E 6BT (GB)
  • LEUNG, Kit-Yi
    London Greater London WC1E 6BT (GB)
  • CASTRO, Sandra
    London Greater London WC1E 6BT (GB)

(74) Representative: Haseltine Lake Kempner LLP 
Cheapside House 138 Cheapside
London EC2V 6BJ
London EC2V 6BJ (GB)

   


(54) AAV-MEDIATED GENE THERAPY OF DISEASES CAUSED BY IMPAIRED FUNCTION OF GLDC