(19)

(11)

EP 4 823 595 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24829079.3 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61K 38/16(2006.01) C07K 14/005(2006.01) A61K 31/7056(2006.01) A61K 31/04(2006.01) A61P 31/04(2006.01) C12N 9/36(2006.01) A61K 31/78(2006.01) (52) Cooperative Patent Classification (CPC): A61K 38/162; C12N 9/2462; A61P 31/04; A61K 9/0034; A61K 9/2054; A61K 9/2018; A61K 9/2027   C-Sets: A61K 38/162, A61K 2300/00; (86) International application number: PCT/EP2024/085960 (87) International publication number: WO 2025/125456 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 EP 23215987 29.08.2024 EP 24197246 06.11.2024 EP 24211117 (71) Applicant: BioNTech SE 55131 Mainz (DE)	(72) Inventors: CORSINI, Lorenzo 55131 Mainz (DE) KIENINGER, Ann-Katrin 55131 Mainz (DE) PODPERA TI ÁKOVÁ, Lenka 55131 Mainz (DE) PROTANO, Maria 55131 Mainz (DE) SCHWEBS, Timo 55131 Mainz (DE) POLJAK, Albina 1030 Wien (AT) (74) Representative: Duncombe, Jessica et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)