(19)
(11) EP 4 823 608 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24841357.7

(22) Date of filing: 13.12.2024
(51) International Patent Classification (IPC): 
A61K 39/12(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 2039/53; C12N 2770/36143; A61K 39/12; C07K 14/005; A61K 2039/55555; C12N 2770/36134; C12N 2770/36122; A61P 31/16; C12N 2760/16134; C12Y 207/07048; C12N 9/127
(86) International application number:
PCT/US2024/060231
(87) International publication number:
WO 2025/129137 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 14.12.2023 US 202363610087 P

(71) Applicant: Amplitude Therapeutics, Inc.
Boston, MA 02210 (US)

(72) Inventors:
  • SAGO, Cory, Dane
    Boston, MA 02210 (US)
  • DINGENS, Adam
    Boston, MA 02210 (US)
  • YANG, Yinmeng
    Boston, MA 02210 (US)
  • MOSAHEB, Mohammad
    Boston, MA 02210 (US)

(74) Representative: Carpmaels & Ransford LLP 
One Southampton Row
London WC1B 5HA
London WC1B 5HA (GB)

   


(54) TWO-COMPONENT PLATFORM FOR TRANS AMPLIFYING RNA (TARNA) VACCINATION