(19)

(11)

EP 4 823 610 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24828775.7 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 37/06(2006.01) A61P 9/00(2006.01) C07K 16/40(2006.01) (52) Cooperative Patent Classification (CPC): C07K 16/40; C07K 2317/76; C07K 2317/565; C07K 2317/567; A61P 9/00; A61P 37/06; A61K 39/3955 (86) International application number: PCT/EP2024/086050 (87) International publication number: WO 2025/125501 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 EP 23216103 (71) Applicant: Eberhard Karls Universität Tübingen, Medizinische Fakultät 72074 Tübingen (DE)	(72) Inventors: GAWAZ, Meinrad 72076 Tuebingen (DE) HEINZMANN, David 72020 Tuebingen (DE) SIGLE, Manuel 72076 Tuebingen (DE) (74) Representative: Witte, Weller & Partner Patentanwälte mbB  Postfach 10 54 62 70047 Stuttgart 70047 Stuttgart (DE)