(19)

(11)

EP 4 823 613 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904871.1 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61K 39/395(2006.01) A61P 29/00(2006.01) A61P 3/00(2006.01) G01N 33/50(2006.01) (52) Cooperative Patent Classification (CPC): A61P 29/00; A61P 3/00; C07K 2317/92; C07K 2317/24; A61K 39/3955; A61K 2039/505; A61K 2039/545; C07K 2317/76; A61K 2039/54; C07K 16/28   C-Sets: A61K 39/3955, A61K 2300/00; (86) International application number: PCT/US2024/059766 (87) International publication number: WO 2025/128818 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 13.12.2023 US 202363609585 P (71) Applicant: Disc Medicine, Inc. Watertown, MA 02472 (US)	(72) Inventors: WU, Min Watertown, MA 02472 (US) XU, Julia Watertown, MA 02472 (US) MACDONALD, Brian Bend, OR 97703 (US) (74) Representative: Atkins, James Gordon John et al Kilburn & Strode LLP Lacon London 84 Theobalds Road London WC1X 8NL London WC1X 8NL (GB)