(19)
(11) EP 4 823 620 A1

(12)

(43) Date of publication:
21.10.2026 Bulletin 2026/43

(21) Application number: 24828140.4

(22) Date of filing: 12.12.2024
(51) International Patent Classification (IPC): 
A61K 45/06(2006.01)
A61P 35/00(2006.01)
A61K 38/12(2006.01)
 C07K 16/28(2006.01)
A61K 39/00(2006.01)
A61K 39/395(2006.01)
(52) Cooperative Patent Classification (CPC):
A61K 2300/00; A61K 45/06; A61K 2039/505; C07K 16/2818; A61P 35/00; A61K 38/12; A61K 39/395; C07K 2317/76
 
C-Sets:
  1. A61K 38/12, A61K 2300/00;
  2. A61K 39/395, A61K 2300/00;
(86) International application number:
PCT/GB2024/053097
(87) International publication number:
WO 2025/125809 (19.06.2025 Gazette 2025/25)
(84) Designated Contracting States:
AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR
Designated Extension States:
BA
Designated Validation States:
GE KH MA MD TN

(30) Priority: 13.12.2023 US 202363609672 P
04.12.2024 GB 202417804

(71) Applicant: BicycleTx Limited
Cambridge CB21 6GS (GB)

(72) Inventors:
  • DICKSON, Amy
    Cambridge CB21 6GS (GB)
  • XU, Cong
    Cambridge CB21 6GS (GB)
  • ARROYO, Santiago
    Cambridge CB21 6GS (GB)
  • HAZARD, Sebastien
    Cambridge CB21 6GS (GB)
  • XU, Lei
    Cambridge CB21 6GS (GB)

(74) Representative: J A Kemp LLP 
80 Turnmill Street
London EC1M 5QU
London EC1M 5QU (GB)

   


(54) BICYCLIC PEPTIDE LIGANDS SPECIFIC FOR NECTIN-4 AND USES THEREOF