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(11)

EP 4 823 642 A1

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(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24904844.8 (22) Date of filing: 11.12.2024

(51) International Patent Classification (IPC):  A61M 1/34(2006.01) A61M 5/142(2006.01) C12M 1/12(2006.01) A61M 1/28(2006.01) B01D 61/24(2006.01) (52) Cooperative Patent Classification (CPC): A61M 1/3489; A61M 2210/1071; C12M 29/10 (86) International application number: PCT/US2024/059674 (87) International publication number: WO 2025/128760 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 US 202363609121 P (71) Applicant: The Medical College of Wisconsin, Inc. Milwaukee, WI 53226 (US)	(72) Inventor: KIM, Joohyun Brookfield, Wisconsin 53045 (US) (74) Representative: Samson & Partner Patentanwälte mbB  Widenmayerstraße 6 80538 München 80538 München (DE)