(19)

(11)

EP 4 823 677 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24840854.4 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61P 25/00(2006.01) C07D 491/04(2006.01) A61K 31/424(2006.01) C07D 405/04(2006.01) C07D 498/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 498/04; C07D 491/04; C07D 405/04; A61P 25/00 (86) International application number: PCT/GB2024/053100 (87) International publication number: WO 2025/125811 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 GB 202318964 24.09.2024 GB 202414004 (71) Applicant: Ontrack Therapeutics Limited Sevenoaks, Kent TN13 1YL (GB)	(72) Inventors: PLOWRIGHT, Alleyn Thomas Cambridgeshire PE8 4LE (GB) PFEIFFER, Thomas London Greater London N19 3UZ (GB) MÄRCHER-RØRSTED, Emil 2300 Copenhagen (DK) DUCKWORTH, Edward Joseph Bristol Avon BS6 5AL (GB) (74) Representative: HGF  HGF Limited 4th Floor, 1 City Square Leeds LS1 2ES Leeds LS1 2ES (GB)