(19)

(11)

EP 4 823 679 A1

(12)

(43) Date of publication: 21.10.2026 Bulletin 2026/43 (21) Application number: 24837771.5 (22) Date of filing: 12.12.2024

(51) International Patent Classification (IPC):  A61P 25/16(2006.01) A61P 37/00(2006.01) C07D 487/04(2006.01) C07D 473/00(2006.01) A61P 25/28(2006.01) C07D 471/04(2006.01) C07D 519/00(2006.01) C07D 513/04(2006.01) (52) Cooperative Patent Classification (CPC): C07D 487/04; C07D 471/04; C07D 473/00; C07D 513/04; A61P 25/16; A61P 25/28; A61P 37/00 (86) International application number: PCT/US2024/059856 (87) International publication number: WO 2025/128873 (19.06.2025 Gazette 2025/25)

(84) Designated Contracting States: AL AT BE BG CH CY CZ DE DK EE ES FI FR GB GR HR HU IE IS IT LI LT LU LV MC ME MK MT NL NO PL PT RO RS SE SI SK SM TR Designated Extension States: BA Designated Validation States: GE KH MA MD TN (30) Priority: 12.12.2023 US 202363609320 P 12.12.2023 US 202363609327 P (71) Applicant: Vigil Neuroscience, Inc. New Jersey 07960 (US)	(72) Inventors: HOUZE, Jonathan B. Morristown, New Jersey 07960 (US) PANDYA, Bhaumik Morristown, New Jersey 07960 (US) (74) Representative: Ipsilon  12 Avenue d'Italie 75013 Paris 75013 Paris (FR)